Results 241 - 250 of about 1337
Original articles in indexed journals - Integrative Biomedical Informatics
Speck-Planche A. Recent advances in fragment-based computational drug design: tackling simultaneous targets/biological effects. Future Med Chem, 2018; 10(17): 2021-2024. PMID: 30058835 . DOI: 10.4155/fmc-2018-0213.
2018
Original articles in indexed journals - GPCR Drug Discovery
Stepniewski TM, Torrens-Fontanals M, Rodríguez – Espigares I, Giorgino T, Primdahl KG, Vik A, Stenstrøm Y, Selent J, Hansen TV. Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists. Bioorgan Med Chem, 2018; 26, 12: 3580-3587. PMID: 29866479 . DOI: 10.1016/j.bmc.2018.05.036.
2018
Original articles in indexed journals - PharmacoInformatics
Radchenko T, Fontaine F, Morettoni L, Zamora I. WebMetabase: cleavage sites analysis tool for natural and unnatural substrates from diverse data source. Bioinformatics, 2018; bty667 . PMID: 30052776 . DOI: 10.1093/bioinformatics/bty667.
2018
Original articles in indexed journals - Computational Science
Skalic M, Varela-Rial A, Jiménez J, Martínez-Rosell G, De Fabritiis G. LigVoxel: Inpainting binding pockets using 3D-convolutional neural networks Bioinformatics, 2018; 35 (2): 243-250 15 . PMID: 29982392 . DOI: 10.1093/bioinformatics/bty667.
2018
Original articles in indexed journals - Computational RNA Biology
Jayasinghe RG, Cao S, Gao Q, Wyczalkowski MA, Sengupta S, Walter MJ and the Splicing Analysis Working Group (including Eyras E). Comprehensive portrait of canonical and non-canonical splicing in cancer. Cancer Research, 2018; 78 (13 Supplement): 2362. DOI: 10.1158/1538-7445.AM2018-2362.
2018
Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics
Aguirre-Plans J, Piñero J, Menche J, Sanz F, Furlong LI, Schmidt HHHW, Oliva B, Guney E. Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology. Pharmaceuticals, 2018; 11(3): E61.. PMID: 29932108 . DOI: 10.3390/ph11030061.
2018
Book chapters - Integrative Biomedical Informatics - PharmacoInformatics
López-Massaguer O, Pastor M, Sanz F, Carbonell P. Hepatotoxicity Prediction by Systems Biology Modeling of Disturbed Metabolic Pathways Using Gene Expression Data. Methods Mol Biol, 2018; 1800: 505-518. PMID: 29934908 . DOI: 10.1007/978-1-4939-7899-1_23..
2018
Book chapters - GPCR Drug Discovery
Rodríguez-Espigares I, Kaczor AA, Stepniewski TM, Selent J. Challenges and Opportunities in Drug Discovery of Biased Ligands. Methods Mol Biol, 2018; 1705: 321-334. PMID: 29188569 . DOI: 10.1007/978-1-4939-7465-8_14..
2018
Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics
Cuadrado A, Manda G, Hassan A, Alcaraz MJ, Barbas C, Daiber A, Ghezzi P, León R, López MG, Oliva B, Pajares M, Rojo AI, Robledinos-Antón N, Valverde AM, Guney E, Schmidt HHHW. Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach. Pharmacol Rev, 2018; 70(2): 348-383. PMID: 29507103 . DOI: 10.1124/pr.117.014753.
2018
Original articles in indexed journals - Computational RNA Biology
Jayasinghe RG, Cao S, Gao O, Wendl MC, Vo NS, Reynolds SM, Zhao Y, Climente-González H, Chai S, Wang F, Varghese R, Huang M, Liang WW, Wyczalkowski MA, Sengupta S, Li Z, Payne SH, Fenyö D, Miner JH, Walter MJ. The Cancer Genome Atlas Research Network, Vincent B, Eyras E, Chen K, Shmulevich I, Chen F, Ding L. Systematic Analysis of Splice-Site-Creating Mutations in Cancer. Cell Rep, 2018; 23(1): 270-281.e3. PMID: 29617666 . DOI: 10.1016/j.celrep.2018.03.052.
2018