Original articles in indexed journals - Systems Pharmacology

Vogt I, Mestres J. Information Loss in Network Pharmacology. Mol Inf, 2019; 38: 1900032. PMID: 30957433 . DOI: 10.1002/ minf.201900032.

2019

Original articles in indexed journals - Evolutionary Genomics

Blevins WR, Tavella T, Moro SG, Blasco-Moreno B, Closa-Mosquera A, Díez J, Carey LB, Albà MM. Extensive post-transcriptional buffering of gene expression in the response to oxidative stress in baker's yeast. Sci Rep, 2019; 9: 11005 . PMID: 31358845 . DOI: 10.1101/501478.

2019

Original articles in indexed journals - NeuroGenomics

Lorente-Galdos B, Lao O, Serra-Vidal G, et al (including Santpere G). Whole-genome sequence analysis of a Pan African set of samples reveals archaic gene flow from an extinct basal population of modern humans into sub-Saharan populations. Genome Biol, 2019; 20(1): 77. PMID: 31023378 . DOI: 10.1186/s13059-019-1684-5.

2019

Original articles in indexed journals - Integrative Biomedical Informatics - Structural Bioinformatics

Aguirre-Plans J, Piñero J, Sanz F, Furlong LI, Fernandez-Fuentes N, Oliva B, Guney E. GUILDify v2.0: A tool to identify molecular networks underlying human diseases, their comorbidities and their druggable targets. J Mol Biol, 2019. pii: S0022-2836 (19) 30117-2.. PMID: 30851278 . DOI: 10.1016/ j.jmb.2019.02.027.

2019

PhD Thesis - Systems Pharmacology

Szabo V. Polypharmacy in the elderly: data, models, and strategies. Universitat Pompeu Fabra. March 13rd, 2019. Thesis Director: Mestres J

2019

Original articles in indexed journals - Functional Genomics

Puigdevall P, Piccari L, Blanco I, Barbera JA, Geiger D, Badenas C, Mila M, Castelo R, Madrigal I. Genetic linkage analysis of a large family identifies FIGN as a candidate modulator of reduced penetrance in heritable pulmonary arterial hypertension. J Med Genet, 2019; 56(7): 481-490. PMID: 30894412 . DOI: 10.1136/ jmedgenet-2018-105669.

2019

Original articles in indexed journals - GPCR Drug Discovery

Sánchez-Melgar A, Albasanz JL^*, Guixà-González R, Saleh N, Selent J, Martín M. The antioxidant resveratrol acts as a non-selective adenosine receptor agonist. Free Radical Biol Med, 2019; 135: 261-273.. PMID: 30898665 . DOI: 10.1016/j.freeradbiomed.2019.03.019.

2019

Original articles in indexed journals - Integrative Biomedical Informatics - Functional Genomics

Gea J, Pascual S, Castro-Acosta AA, Hernández-Carcereny C, Castelo R, Marquez-Martin E, Montón C, Palou A, Faner R, Furlong LI, Seijo L, Sanz F, Torà M, Vilaplana C, Casadevall C, López-Campos JL, Monsó E, Peces-Barba G, Cosio BG, Agustí A, Anexo. Miembros del grupo BIOMEPOC. The BIOMEPOC Project: Personalized Biomarkers and Clinical Profiles in Chronic Obstructive Pulmonary Disease. Arch Bronconeumol, 2019; 55(2): 93-99. PMID: 30343952 . DOI: 10.1016/j.arbres.2018.07.026.

2019

Original articles in indexed journals - Computational Science

Skalic M, Jiménez Luna J, Sabbadin D, De Fabritiis G. Shape-Based Generative Modeling for de-novo Drug Design. J Chem Inf Model, 2019; 59 (3): 1205-1214. PMID: 30762364 . DOI: 10.1021/acs.jcim.8b00706.

2019

Original articles in indexed journals - Computational RNA Biology

Bueno C, Velasco-Hernandez T, Gutiérrez-Agüera F, Zanetti SR, Baroni ML, Sánchez-Martínez D, Molina O, Closa A, Agraz-Doblás A, Marín P, Eyras E, Varela I, Menéndez P. CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicity. Leukemia, 2019; 33, 2090-2125. PMID: 30778134 . DOI: 10.1038/s41375-019-0418-8.

2019